Aromatase inhibitors in post-menopausal endometriosis
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چکیده
منابع مشابه
Aromatase inhibitors in post-menopausal endometriosis
Postmenopausal endometriosis is a rare clinical condition. The diagnosis and treatment of an endometriotic lesion in postmenopausal women is complicated. First line treatment choice should be surgical, given that there is a potential risk of malignancy. Medical treatment may be considered as second line or as an alternate first line treatment whenever surgery is contradicted and aims to alter t...
متن کاملAromatase inhibitors in the treatment of endometriosis.
Endometriosis is a chronic inflammatory condition in which foci of endometrial tissue grow outside of the uterine cavity. Endometriosis was estimated to affect 176 million women of childbearing potential all over the world in 2010. The presence of extrauterine endometrial tissue is associated with pain and infertility. Typical symptoms of endometriosis include dysmenorrhoea, dyspareunia, heavy ...
متن کاملPotential role of aromatase inhibitors in the treatment of endometriosis
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متن کاملPotential role of aromatase inhibitors in the treatment of endometriosis
Endometriosis is an estrogen-dependent chronic inflammatory disease affecting 5%-10% of reproductive-age women, with a prevalence of 5%-50% in infertile women and >33% of women with chronic pelvic pain. Third-generation aromatase inhibitors (AIs) are approved adjuvants for the treatment of estrogen receptor-positive breast cancer. Molecular studies have revealed the presence of aromatase P450, ...
متن کاملMolecular basis for treating endometriosis with aromatase inhibitors.
Although treatment of one unusually aggressive case of postmenopausal endometriosis with an aromatase inhibitor has been strikingly successful, large clinical trials are required to establish whether aromatase inhibitors will have a significant role in the medical management of endometriosis. Introduction of aromatase inhibitors into the treatment of endometriosis underscores the importance of ...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2011
ISSN: 1477-7827
DOI: 10.1186/1477-7827-9-90